MERCEDES W221 Parts & S-CLASS Aftermarket

The Mercedes-Benz W221, produced between 2005 and 2013, represents the fifth generation of the S-Class luxury sedan, combining advanced technology with high-end comfort. W221 Parts encompass a comprehensive range of components designed for maintenance, repair, and performance enhancement in the aftermarket. These parts cover major vehicle systems including the engine, suspension, braking, transmission, electrical, and body components, ensuring that the vehicle maintains its original performance and reliability standards.

Engine parts for the W221 include cylinder heads, camshafts, pistons, timing chains, and turbochargers for both petrol and diesel variants. These components are critical for ensuring optimal combustion, power delivery, and fuel efficiency. High-quality aftermarket engine parts are manufactured to meet OEM standards, providing durability and precise fitment for workshops and parts suppliers.

Suspension and chassis components play a vital role in maintaining ride comfort and vehicle handling. W221 Suspension Parts include air suspension struts, control arms, bushings, shock absorbers, and stabilizer links. These parts are especially important as the W221 features the AIRMATIC air suspension system, which requires precise calibration and reliable components to preserve its smooth and adaptive ride characteristics.

Braking system parts are another key category. Aftermarket brake discs, pads, calipers, and ABS sensors ensure that the W221 maintains safe stopping power under all conditions. High-quality replacement parts help workshops provide consistent braking performance while minimizing noise and wear.

The W221’s electrical and electronic systems are also extensive, covering items such as ECU modules, sensors, wiring harnesses, lighting units, and infotainment components. Given the W221’s advanced features, including adaptive cruise control, lane assist, and COMAND system, reliable aftermarket electrical parts are crucial for ensuring system stability and seamless operation.

Body and trim parts allow for aesthetic maintenance and accident repair. Front and rear bumpers, fenders, grilles, and interior panels help maintain the vehicle’s premium appearance. Using genuine-fit aftermarket body parts ensures correct alignment, color matching, and long-term durability.

Overall, W221 Parts cater to a wide network of suppliers, repair shops, and enthusiasts focused on keeping these luxury vehicles in peak condition. Aftermarket parts for the W221 are designed with precision and reliability, meeting the expectations of demanding workshops and procurement specialists. By providing a comprehensive selection of engine, chassis, brake, electrical, and body components, suppliers help extend the life of the W221 while maintaining its high performance, safety, and comfort standards.

For distributors and parts wholesalers, W221 Parts offer a consistent demand due to the model’s global popularity and the need for regular maintenance and replacement. Quality, compatibility, and availability are key factors, ensuring that aftermarket parts effectively support workshops and service providers in keeping these iconic Mercedes-Benz sedans operational and luxurious.

Search results: MERCEDES w221 parts Hot list of this issue
2700501200 Engine Parts Rocker Arm for MERCEDES-BENZ R-CLASS, BRABUS 50S (W221)
2700501200 Engine Parts Rocker Arm for MERCEDES-BENZ R-CLASS, BRABUS 50S (W221)
OE:
270 050 12 00
CAT:
Camshaft
ID:
MERCEDES w221-65886
a6420901686 Turbocharger for MERCEDES-BENZ GLE Coupe (C292), CLS (C218), E-CLASS T-Model (S212), S-CLASS (W221), GL-CLASS (X166), M-CLASS (W166)
a6420901686 Turbocharger for MERCEDES-BENZ GLE Coupe (C292), CLS (C218), E-CLASS T-Model (S212), S-CLASS (W221), GL-CLASS (X166), M-CLASS (W166)
OE:
a6420901686
CAT:
Turbocharger
ID:
MERCEDES w221-54050
a2215458732 ABS Pump for MERCEDES-BENZ S-CLASS (W221)
a2215458732 ABS Pump for MERCEDES-BENZ S-CLASS (W221)
OE:
a2215458732
CAT:
ABS Sensor
ID:
MERCEDES w221-53012
2215450714 Engine Parts Start/stop Switch Cover for MERCEDES-BENZ C-CLASS (W204), CLA Coupe (C117), GLA-CLASS (X156), SL (R231), SLC (R172), B-CLASS Sports Tourer (W246, W242), S-CLASS (W221), GLC (X253), GLE Coupe (C292), GLS (X166), A-CLASS (W176),
2215450714 Engine Parts Start/stop Switch Cover for MERCEDES-BENZ C-CLASS (W204), CLA Coupe (C117), GLA-CLASS (X156), SL (R231), SLC (R172), B-CLASS Sports Tourer (W246, W242), S-CLASS (W221), GLC (X253), GLE Coupe (C292), GLS (X166), A-CLASS (W176),
OE:
221 545 07 14
CAT:
Others
ID:
MERCEDES w221-42596
2218706758 Blower Motor Resistor for MERCEDES-BENZ S-CLASS (W221)
2218706758 Blower Motor Resistor for MERCEDES-BENZ S-CLASS (W221)
OE:
221 870 67 58
CAT:
Air Blower
ID:
MERCEDES w221-42284
2223600175 Transmission Parts C.V Joint for MERCEDES-BENZ S-CLASS (W221), CLS (C218), E-CLASS (W212), C-CLASS (W204), GLK-CLASS (X204)
2223600175 Transmission Parts C.V Joint for MERCEDES-BENZ S-CLASS (W221), CLS (C218), E-CLASS (W212), C-CLASS (W204), GLK-CLASS (X204)
OE:
222 360 01 75
CAT:
C. V Joint
ID:
MERCEDES w221-42211
2780101728 Engine Parts Oil Pan for MERCEDES-BENZ S-CLASS (W221)
2780101728 Engine Parts Oil Pan for MERCEDES-BENZ S-CLASS (W221)
OE:
278 010 17 28
CAT:
Oil Sump
ID:
MERCEDES w221-42172
2215012791 Engine Parts Cooling Water Pipe for MERCEDES-BENZ S-CLASS (W221)
2215012791 Engine Parts Cooling Water Pipe for MERCEDES-BENZ S-CLASS (W221)
OE:
221 501 27 91
CAT:
Cooling Pipe
ID:
MERCEDES w221-42149
2215012691 Engine Parts Cooling Water Pipe for MERCEDES-BENZ S-CLASS (W221)
2215012691 Engine Parts Cooling Water Pipe for MERCEDES-BENZ S-CLASS (W221)
OE:
221 501 26 91
CAT:
Cooling Pipe
ID:
MERCEDES w221-42148
2214708494# Engine Parts Fuel Pump for MERCEDES-BENZ S-CLASS (W221), VITO Bus (W638)
2214708494# Engine Parts Fuel Pump for MERCEDES-BENZ S-CLASS (W221), VITO Bus (W638)
OE:
221 470 84 94#
CAT:
Electrical Fuel Pump
ID:
MERCEDES w221-41579
2722000415 Engine Parts Thermostat for MERCEDES-BENZ S-CLASS (W221), SLK (R171), E-CLASS T-Model (S211), M-CLASS (W164), C-CLASS T-Model (S203), GLK-CLASS (X204), R-CLASS (W251, V251), CLC-CLASS (CL203), CLS (C219), SL (R230), VALENTE Bus (W639), VIT
2722000415 Engine Parts Thermostat for MERCEDES-BENZ S-CLASS (W221), SLK (R171), E-CLASS T-Model (S211), M-CLASS (W164), C-CLASS T-Model (S203), GLK-CLASS (X204), R-CLASS (W251, V251), CLC-CLASS (CL203), CLS (C219), SL (R230), VALENTE Bus (W639), VIT
OE:
272 200 04 15
CAT:
Thermostat
ID:
MERCEDES w221-41560
6512006401 Engine Parts Water Pump for MERCEDES-BENZ METRIS Van (W447), METRIS Tourer (W447), E-CLASS Coupe (C207), V-CLASS (W447), MARCO POLO Camper (W447), GLK-CLASS (X204), C-CLASS (W204), CLS (C218), S-CLASS (W221)
6512006401 Engine Parts Water Pump for MERCEDES-BENZ METRIS Van (W447), METRIS Tourer (W447), E-CLASS Coupe (C207), V-CLASS (W447), MARCO POLO Camper (W447), GLK-CLASS (X204), C-CLASS (W204), CLS (C218), S-CLASS (W221)
OE:
651 200 64 01
CAT:
Water Pump
ID:
MERCEDES w221-41291
6422001156 Engine Parts Pipe Connector for MERCEDES-BENZ X-CLASS (470), GLE Coupe (C292), GLS (X166), CLS (C219), E-CLASS T-Model (S211), GL-CLASS (X164), GLK-CLASS (X204), G-CLASS Cabrio (W463), C-CLASS (W203), M-CLASS (W164), S-CLASS (W221), R-CLAS
6422001156 Engine Parts Pipe Connector for MERCEDES-BENZ X-CLASS (470), GLE Coupe (C292), GLS (X166), CLS (C219), E-CLASS T-Model (S211), GL-CLASS (X164), GLK-CLASS (X204), G-CLASS Cabrio (W463), C-CLASS (W203), M-CLASS (W164), S-CLASS (W221), R-CLAS
OE:
642 200 11 56
CAT:
Cooling Pipe
ID:
MERCEDES w221-41216
6421880480 Engine Parts Gasket oil Cooler for MERCEDES-BENZ SPRINTER 5-t Van (B906), E-CLASS T-Model (S211), GLE Coupe (C292), GLS (X166), GLC Coupe (C253), CLS (C219), S-CLASS (W221), GL-CLASS (X164), GLK-CLASS (X204), C-CLASS (W203), M-CLASS (W164)
6421880480 Engine Parts Gasket oil Cooler for MERCEDES-BENZ SPRINTER 5-t Van (B906), E-CLASS T-Model (S211), GLE Coupe (C292), GLS (X166), GLC Coupe (C253), CLS (C219), S-CLASS (W221), GL-CLASS (X164), GLK-CLASS (X204), C-CLASS (W203), M-CLASS (W164)
OE:
642 188 04 80
CAT:
Oil Cooler
ID:
MERCEDES w221-41152
2720520216 Engine Parts Guide Rail for MERCEDES-BENZ S-CLASS (W221), E-CLASS T-Model (S211), M-CLASS (W164), G-CLASS (W463), C-CLASS T-Model (S203), GLK-CLASS (X204), R-CLASS (W251, V251), CLS (C219), SL (R230), SLK (R171), CLC-CLASS (CL203), VALENTE
2720520216 Engine Parts Guide Rail for MERCEDES-BENZ S-CLASS (W221), E-CLASS T-Model (S211), M-CLASS (W164), G-CLASS (W463), C-CLASS T-Model (S203), GLK-CLASS (X204), R-CLASS (W251, V251), CLS (C219), SL (R230), SLK (R171), CLC-CLASS (CL203), VALENTE
OE:
272 052 02 16
CAT:
Timing Parts
ID:
MERCEDES w221-40427
2213300225 Transmission Parts Wheel Bearing for MERCEDES-BENZ S-CLASS (W221)
2213300225 Transmission Parts Wheel Bearing for MERCEDES-BENZ S-CLASS (W221)
OE:
221 330 02 25
CAT:
Wheel hub
ID:
MERCEDES w221-39721
0009959710 4Pins Engine Turbo Air Intake Duct for MERCEDES-BENZ GLS (X166), GLE Coupe (C292), CLS (C218), E-CLASS (W212), S-CLASS (W221), GLK-CLASS (X204), GL-CLASS (X164), G-CLASS (W463), M-CLASS (W164), C-CLASS (W204), R-CLASS (W251, V251)
0009959710 4Pins Engine Turbo Air Intake Duct for MERCEDES-BENZ GLS (X166), GLE Coupe (C292), CLS (C218), E-CLASS (W212), S-CLASS (W221), GLK-CLASS (X204), GL-CLASS (X164), G-CLASS (W463), M-CLASS (W164), C-CLASS (W204), R-CLASS (W251, V251)
OE:
000 995 97 10
CAT:
Air Filter
ID:
MERCEDES w221-39365
2760502900 Engine Parts Tensioner, Timing Chain for MERCEDES-BENZ GLC (X253), E-CLASS T-Model (S212), S-CLASS (W221), SLC (R172), C-CLASS (W204), GLE Coupe (C292), GLS (X166), SL (R231), GL-CLASS (X166), CLS (C218), M-CLASS (W166), GLK-CLASS (X204),
2760502900 Engine Parts Tensioner, Timing Chain for MERCEDES-BENZ GLC (X253), E-CLASS T-Model (S212), S-CLASS (W221), SLC (R172), C-CLASS (W204), GLE Coupe (C292), GLS (X166), SL (R231), GL-CLASS (X166), CLS (C218), M-CLASS (W166), GLK-CLASS (X204),
OE:
276 050 29 00
CAT:
Belt & Tensioner
ID:
MERCEDES w221-38999
6420942404 Engine Parts Air Filter for MERCEDES-BENZ GLS (X166), GLE Coupe (C292), E-CLASS Coupe (C207), G-CLASS Cabrio (W463), CLS (C218), S-CLASS (W221), M-CLASS (W164), GL-CLASS (X164), GLK-CLASS (X204), C-CLASS T-Model (S204), R-CLASS (W251, V251
6420942404 Engine Parts Air Filter for MERCEDES-BENZ GLS (X166), GLE Coupe (C292), E-CLASS Coupe (C207), G-CLASS Cabrio (W463), CLS (C218), S-CLASS (W221), M-CLASS (W164), GL-CLASS (X164), GLK-CLASS (X204), C-CLASS T-Model (S204), R-CLASS (W251, V251
OE:
642 094 24 04
CAT:
Air Filter
ID:
MERCEDES w221-38433
2781840080 Engine Parts Oil Cooler Gasket for MERCEDES-BENZ M-CLASS, BAIC-ORV BJ90, BRABUS 50S (W221)
2781840080 Engine Parts Oil Cooler Gasket for MERCEDES-BENZ M-CLASS, BAIC-ORV BJ90, BRABUS 50S (W221)
OE:
278 184 00 80
CAT:
Oil Cooler
ID:
MERCEDES w221-38409
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